I'm on my second New Vegas playthrough and this time I want to play an evil character. The trouble is that I occasionally get good karma from killing raiders and fiends that attack me. I already know that I could simply run into an innocent town and slaughter everybody in sight but I don't want to do that - I like having as many merchants, doctors, quest givers, and caravan players available to me as possible. That doesn't mean that I won't kill any innocents, it's just that I don't know where I can kill innocents without turning the rest of the town or faction hostile to me. Also, is there a place with an infininte amount of innocent people who regenerate every few days? I don't want to make everywhere a ghost town, either.
I also know that I could just steal everything not bolted to the floor but that gets tedious after a while because I think the karma loss is minimal, and I also think it's kind of ridiculous to lift junk off of someone just for the sake of karma loss, then turn right around and put everything back where it was because I looted a bunch of stuff I don't want in the first place (like toy cars and tin cans).