The muffle spell trains illusion very fast (even if your not in combat), if you don't want to exploit the game then just use the manipulation spells (fury, fear, calm etc) on every enemy you come across. Make use of the spells that increase the defense of allies.
You need to be dual casting your illusion spells for them to be effective. Then you will need to invest in all the perks in the right side of the tree, you can avoid silent casting if you aren't sneaking. When you have the relevant perks and you dual cast your illusion spells, you will be able to use the basic fury/calm/fear on everything that isn't immune to illusion.
I use these basic spells all the time (level 59), and I've only come across some mercenaries that were to high a level for my basic spells, but the frenzy spell worked on them. The master spells are an absolute waste of time at high levels, you can't dual cast it so it doesn't affect anything strong.
Little tip that I found helpful, the most useful spell is fury/frenzy for groups, cast it on the strongest person in that group and then the enemies will usually focus on him rather than you (higher priority I assume). When you are faced with one enemy, fear is the way to go. Just fear and you can keep hitting them whilst they sit there cowering.
Hope that helps

Edit: I believe dual casting does 2.2 the effect, for 2.8 times the cost.