I never had this problem before I installed Honest Hearts, but suddenly the game crashes every minute or two. 5-10 minutes between crashes if I'm lucky. The only thing that changed between the last time I played FNV and now is I installed Hunted: Demon's Forge and stopped the services for my FTP and Ventrilo servers. The game is now completely unplayable for me. Sometimes it crashes so quick I spend more time starting the game and loading my save than I do playing. No other games or applications have crashed on my system in a very long time, either. I'm going to have to try copying my save files over to my laptop and playing from there. This is completely absurd.

welcome to New Vegas

Same thing happened to me with Point Lookout on Fallout 3, if you're on a console you should be able to unload it and reload whenever you want to...don't expect to be bug free if you reload it... :shrug:

the bigger your save is, the worse it gets