1. Objects in the world not loading correctly. After loading a save, objects in the world seem to drop out of the sky within a second.
2. AI is sometimes stuck under the floor.
3. When in danger, the AI (that is supposed to be attacking you) sometimes ignores you and just runs around like a chicken with its head chopped off.
4. AI easily gets stuck onto objects or anything part of the environment when they are trying to attack you.
5. After killing the Jackal gang at the ruins, half way to Nipton, from long distance Jacklyn suddenly appears and runs to your location after, according to her, killing a would-be robber. I am assuming that I was supposed to witness this event upon arrival to Nipton? Please note that I am only half way to Nipton when she comes and talks to me.
6. Every time I use the pipboy to fast travel to Good Springs there is always a living rad scorpion in front of the bar.

This is all I can think of at the top of my head, besides the common bugs everyone else is experiencing.

so are you crashing when buying from merchants too? especially mass purchases