This is my third playthrough. I haven't seen any major or even minor glitches in my relatively short time playing... that is, until I reached the golden claw door at Bleak Falls Barrow. I didn't have any trouble here the first two times, but for some reason the outer, middle and inner rings to the door won't move this time. Not at all. Sure I can put the dragon claw itself into the door no problem, but if I can't move the three rings I can't breach this door, the main quest is over before it even begins.

I think I'll play Morrowind now, but I'll be waiting for feedback anyway.

Edit: Also, this is my first playthrough with the Dawnguard expansion. Hmmmm...