I have encountered a MAJOR glitch within the game, one than even prevents me from getting a certain achievement (im playing it on Xbox 360). Here is my problem:

I got early on ED-E as a follower. Everything was going fine at first. I unlocked a conversation with him at the Scarpyard, and a second time at Helios One. When it came time for the third conversation (when you listen to Lorenzo's message), once the conversation was done my character simply froze! Not the game, my character. I was already 30 hours in the game at this point. I was able to look around normally, but I couldnt walk anywhere, I couldnt lift my gun up, I couldnt look at my Pip-Boy. Basically I couldnt do anything but look around. I loaded a previous save but this glitch happened everytime (i tried at least 8 times) and I could not avoid it because ED-E came to talk to me automatically. From here I tried several ways to get around this glitch. At first, I simply told ED-E to stay there before he can come talk to me. However, he was holding several of my unique weapons that i wanted to take back if I was to go wonder around without him. When i tried to get my equippment back, it would only result by him talking to me again and freezing my character in place. So then I thought i would temporarily turn the game to hardcoe mode and kill him and retreive my weapons from the debris. However when we exploded, he left no pieces on the floor for me to re-aquire my items. So finally I decided to just leave him there, with my unique weapons, and continue the game without him (hoping the game update would fix this problem and I could go back and get my weapons).

Everything was fine until i was about 45 hours in the game, when i was exploring Vault 22. When I entered a new area within the vault (requiring a load screen), for some reason ED-E magically re-appeared out of nowhere and started to attack my enemies (after which the enemies were dead, the same dreaded conversation occured resulting in my character freezing). So I had the brilliant idea to quickly take back all my weapons from ED-E before killing him (by turning back on hardcoe mode for a few brief seconds) while he was occupied fighing the enemies. Finally I tought i had gotten past this problem for good. I had my weapons and ED-E was dead and not comming back

Now, in my 70th-hour of the game, it came back to bite me in the ass once again. I was attempting to recruit Rex the dog as a follower but we wouldnt because he was ''growling at ED-E'' and it couldnt follow because apparently, according to the game, I still had ED-E as a follower.....but I had killed him almost 30 hours ago.... Now I cannot get the achievement to recuit all followers because I can never recuit Rex!

This is VERY fustrating because I was eventually going to attempt to get all the achievements. I was able to deal with the other minor glitches but this one is unacceptable because it changes the way i have to play the game and I cannot accomplish certain side-quests. Has anyone encountered this problem? or similar problems? I hope Bethesda reads this and adresses it.