I met what I expected to meet. So I'm fine. Really.
Plus Tenpenny was already the "Howard Hughes" type character.
No he wasn't. Other than "wacky rich guy with urination issues". ^_^
House lacks the complete criminal intent of your other examples, too. He's OCD, he's extremely reclusive, he delves into his creation of dreams like very possibly nobody else before him (those did rightfully so), giving up society and more in the process... And there is that little fact of which city he wants to build into something glamorous.
Saying he's Hughes' very exaggerated likeness, only fitting for the Fallout world, would not be very wrong. ^_^