I have been watching the Gophervids stuff for Skyrim Mod Sanctuary and very early on he talks about two mods that help to increase performance (4gb skyrim and borderless windows player). My question is whether better alternatives to these are now available since the creation kit has been released?
I know there are some graphics mods that decrease the textures in-game. So if you have a weaker graphics card, that would help. I can't remember the name, but there was a thread here a while ago.
There are tools like http://skyrim.nexusmods.com/mods/12801 that can be used to reduce the size of textures by applying a different compression and/or resizing the texture.