This is a great example, I'd forgotten about that completely.
A major benefit for something like this is that it makes money valuable, it gives you plenty of progressively more expensive options to throw your money at, making money more valuable, and the game more immersive. Look at GTA4 for example, you have to wonder why money was even implemented, after the first couple missions you never have to worry about it again.
And to everyone saying this isn't 'sim city', I realize this, it's a role-playing game. A good role playing game offers multiple avenues for accomplishing tasks. If you want to play the gun toting moron just running around shooting everything in the head, I wonder why you're here. Granted, it's fun, but it's also in, you know, EVERY FPS out there. This is a hybrid game, a role playing game, I see no reason to discredit someone's idea for possible new roles to fill because they don't suit your personal play-style, Especially when the idea isn't even detracting from your ability to pursue your style.
Dev. and forumers listen to this man. God gave him a good head on his shoulders. Just because you dont want to run a casino (wich if it was in game you know you would love it) does not mean that you can say somthing without thinking threw it first. I think a casino would add even more to the lore. At the begining it could be a run down yuck of a building. You might get that occasional dude that needs to stay somewhere over night. After you get enough money you could repair the building, get guards, by walls, furnish the inside, hire entertainment from places around the wasteland (Just go to say the strip and find someone on the street... after talking to them you pay them a few caps and they come to work as security, entertainment, waiter, etc.) Get new games, compete with other casinos, get attacked by the ocassional raiders, oposing faction, etc. (That also brings up, depending what faction you join they will start to hang around and lend you a hand with the casino.) You could get money from the manager wich you hire when you get your building. The money will come as more people arrive, and as you upgrade you will see more people coming... eventually a caravan will put you on its route, and deliver goods to your casino.