No, first you would experience chronic fatigue. Then you'd suffer hallucinations and psychotic episodes. Finally, there's severe mental illness and handicap akin to Alzheimer's followed by death.
Only if there's something wrong with you. Granted, extreme sleep deprivation has a variety of effects, and I'd imagine these can be catalysts for countless other conditions.
The human brain is -supposed- to override and take microsleeps (which is (one reason) why driving while tired can be so dangerous)
Lesser developed brains (lab mice, for example) do not have this function and can die if placed into an apparatus (eg, http://upload.wikimedia.org/wikipedia/commons/f/fd/Sleep-deprivation-flowerpot-technique-jepoirrier.jpg)
Perhaps the courier's gunshot wounds broke something