When you have brought three NPC companions to reform the Blades you get your first quest (from Esbern) to find a dragon-lair and kill a dragon with the help of the new Blades. When you come back Esbern tells you to get a dragon bone and scale for him to study in order to create something helpful "the scale from the Argonian that bit you"... so you get the quest called "bring a dragon bone and a dragon scale to Esbern".
When you deliver them the quest completes, you get a potion called "Esbern's Potion", which should give the "dragon infusion perk" (dragons do 25% less damage to you).. however, the quest remains in your log (doesn't track or let you click it) and the potion does nothing when consumed.
Also on a side note... if you bring the female companion from the theives-guild-town after you get her magical sword from the Dwemer ruins, she will kill the other two blades while sparring in the courtyard due to the magical damage she does... so take that sword from her as soon as she gets there (and never give any weapons that does magical damage).
Please patch this.

