» Sat Jun 16, 2012 3:17 pm
I assume you're looking for an answer like this:
Cast Bound Bow, apply poison of weakness to X, shoot bandit with poisoned arrow, switch to Destruction spell with corresponding element. If you were cautious, you'd do as many have said and cast a rune before all of this.
Of course if the first two bandits are weak, you'd just kill them with the bow.
But people have a point - if you're using your Bound Bow, you probably won't have much need for Destruction spells. If you're using a Bound Bow with poison, even less so. By the time you can find and cast Bound Bow, your Conjuration is usually pretty decent, and you may have the perk that increases the bow's damage.
Conversely, if you're relying on Destruction, it's a little wonky to summon a bow and use it as a poison delivery system, all before casting your spells. Casting the bow eats up your precious Magicka reserves, which you desperately need as a Destruction mage unless you're deep into cost-reduction enchantments. More importantly, casting and using the bow takes time. In the amount of time it takes you to cast, draw, and shoot your Bound Bow, you could have cast several Destruction spells, which arguably negates the effectiveness of the bow as a poisoning mechanism.
I have nothing against mixing Archery with Destruction - in fact, I have an Arcane Archer around lvl 33 who is a beast - but you usually want to really pump up one or the other, not both. My preferred method for my Arcane Archer is to open with a rune, then switch to my (enchanted) bow. Destruction is just there for a little extra 'oomf', and for when enemies get too close (though ever since I grabbed Ranger, that pretty much never happens anymore).