I've tried running it in windowed mode set to 1152x864, and it runs better. Most of my settings are set to the minimum amount possible, except texture quality, which is set to medium.
Another problem I have is mouse acceleration, is there a way to turn it off? That would make the game a lot easier to play in windowed mode.
Oh, and don't bother telling me to buy a better computer, I know it's [censored]. But I'm a stubborn bastard when it comes to Skyrim.
