If you reinstall Skyrim and remove all your mods, but keep your saves and then load your saved game that previously had mods, should there be any mod effects left in the game?
I did this and some guards were still altered by a mod I removed and the grass textures still looked altered from Vurt's Flora Overhaul. Neither mods were active.
Yes, some mods' changes are written to a save file, so some effects may be possible. I once in Fallout 3 got a bug from an overhaul i wasn't using after a clean install because i used a start of the game save where i had had it installed