Specifically Karthwasten Hall. Is the storage there safe?

Any house should be safe, I still have all my items in my bedroom chest inside of Breezehome. Where i live with my spouse ^.^

I think he means the houses that you can move into with your spouse. Like Ysolda's House.

I've used K hall for storage once wed to (insert traditional Breton name here) and have never come across problems. Mind you, I've read people saying the respawn time for certain cells is ten (in-game) days. I'd suggest sleeping that time off somewhere distant with a backed up save to test. I looked on UESP for any bug lists for K hall and found nothing.

Checking the CS, The barrels are not safe but the other storage is.

Thanks guys. I appreciate it.