i am having the same problem now. was working fine last night when i played it, but this afternoon ive booted up my pc to play and firstly it isnt even recognizing my toolbar icon anymore and when i go through the long route of opening it up, all it keeps doing to me when i click on play is bring up a windows control box which asks me if i want to allow the program to make changes to my pc. everytime i click on yes it just goes back to the skyrim options box, so i click play again and the same control box pops up and round and round we go in the same loop. just for the record i have no mods running at all. i always have steam set to offline mode,because i really dont trust it and as far as i am aware the last patch it updated to was 1.3. i desperately need help now as all this broken crap is starting to get rediculous. i thought after 1.3 fixed all my issue problems it was going to be fine and now this!?! please, please help, anyone!
Go to your steam folder, then steamapps/common/skyrim
Now right click TESV.exe, then go to compatibility and uncheck the boxes if any are checked. Such as run as administrator, or run in Windows XP compatibility mode etc etc.
Repeat this for skyrimlauncher.exe also.
Then try to launch the game in steam again. If you've done it right it will not ask you if you want to make changes to your computer.