Well, i just made a new Warrior char yesterday and was building his One Handed/Two Handed up, and was wondering if the Skull Smasher/Bone Breaker perks are even useful against non Humanoid NPCs. Do creatures like Wolves, Frost Trolls, Giants and Dragons even have an Armor Rating to reduce?
I like the idea of my Nord Warrior specializing in Blunt weps and using Mace of Molag Bal+Spell Breaker for 1H+Shield, and Volendrung for 2 Hander, but would like to know if it's only useful against Humanoid NPCs. I've noticed not alot of Humanoid NPCs are heavily armored either, certainly not like wearing full suits of Daedric or such.

Only humanoids that wear armor have any armor rating. Dragons, mammoths, giants, draugr all have an armor rating of 0.

And yes, it's very rare to meet anyone with more than 200 points of armor. It's mostly bandit chiefs or the occasional sword n board bandit in iron armor that gets that high.

^this.

Save the perks, those are really wasted unfortunately. The axe and sword perks are not much better either

Bah, that svcks. You'd think that at least Dragons would have an Armor Rating, considering their Scales/Bones are hard enough for us to make some great armor out of.
Maybe that's a way they can balance between the damage of a Warrior and Destruction Mage. Instead of giving creature's huge, excessive health pools, give them Armor Rating. That way, a Mage who's consuming Magicka would be dealing unmitigated damage (Assuming he's using the appropiate element for the creature), while a Warrior's weapon strikes would be going up against damage mitigation. Would balance the huge damage difference between Weapons and Magic. If a Warrior wanted to reduce the damage mitigation, he'd have to perk for and use the slowest weapons in the game (Besides Volendrung, which swings at the same speed or faster than a Great Sword, which hopefully they don't fix. In previous TES games, Volendrung granted/absorbed Strength, which logically would make the weapon easier/faster to swing.)