Well obviously... but then I'm not really one to try using everything at once.
Alteration and Restoration are almost useless if you don't get hit... and even so, I only ever use Restoration rarely after the occasions when I DO get hit... assuming I don't die first.
So that leaves Conjuration, Destruction and Illusion... each a valid means of defeating the enemy... but not really effective to juggle together. Best to pick one and stick with it.
Restoration is pretty good against undead, you can make them flee, and use the already dead undead to chase after said fleeing undead, its pretty funny. I just like variety. Alteration is good for paralysis as well, and water breathing is good for escaping those damned chauruses in the swamps....the master restoration spell makes me laugh , makes all undead catch on fire, run away and explode, lol.