I'm thinking of going with ST at 4 and taking the perk Weapon Handling (-2 Weapon ST requirements) at level 16. I read somewhere that sniper rifles require ST 6 (4 with WH) and I don't think I'll need more (not fond of big guns).
EDIT: Some weapon entries in the Fallout Wiki list the strength requirements but not all of them. I would like to have a complete list.
