Yes, few modders allready done that (its not so popular as landscapes)
For example > this mod have separate folder for all retextures + pictures
Skyrim Redesigned
http://www.skyrimnexus.com/downloads/file.php?id=2550
or
Tobes Highres Textures
http://www.skyrimnexus.com/downloads/file.php?id=1123
or some others textures overhauls, mostly with "Clutter" in names
http://www.skyrimnexus.com/downloads/file.php?id=3600
Dont forget to add some matching wine bottles too

http://www.skyrimnexus.com/downloads/file.php?id=4260