It is very worth it. Being a werewolf is awesome.

You can cure yourself, but why would you.
You don't get resting bonus' but they don't matter anyway.
That's the only thing you don't get as a werewolf. Nothign else.
There are no drawbacks and you can kill or assasinate people as a werewolf without getting a bounty because they don't know it's you.
Don't get seen changing, charge in, kill the target, run away out of the town, etc, keep running till you are not in danger then wait to change back were you can't be seen.