If I can have a nice assault rifle, perhaps with an underbarell grenade launcher, and enough ammo I will be happy to have nothing else.
Looks like you're gonna need mods for that mate, since we ain't seen anything of the such yet.
OP: I reckon the wingstick looks the most satisfying, hopefully it can get an explosive upgrade, if not then I'll just mod it. The Settler Assault Rifle looks like my primary weapon for most scenarios, with a bit of shotgun in close-combat.