I find it unlikely for a couple of reasons.
The Race of the Dragonborn will be left a mystery, much like the Race of the CoC and the Nerevarine was never mentioned after the event. This makes it very hard to narrow it down to a potential bloodline that could follow. They could go with the standard Imperial royal family, but that would, fromm what we know about mating in TES, either limit the gender to male and race to Elven or Human. Of cours this is a fairly broad spectre, but it is only one of the option.
If we imagine the Dovahkiin as female we would have to limit said Hero's race to the race of their decendants, which impose a much more strict and solid information. To have solid information about who and what the Heroes of the main ES games were would be breaking a tradition going back to the very first game.
The race issue will also almost certainly limit the race possibilities a canon Dovahkiin to Nord, Imperial and Breton seeing as they are the ones who traditionally have ruled the Empires.
From a lore standpoint it seems very unlikely that it can happen. Shivering Isles spoiler:
Spoiler It is not like when you took the role of Sheogorath which meant that you would mantle his power and become him over time, changing into the role.
The second argument against it is from a gameplay perspective. As Emperor there would have to be a major overhaul in the machanics in the game since they are not designed to be used in a game were you govern an Empire or Kingdom. If you ebcome Emperor you would have to have a near constant presense in the Imperial Palace and you would be largely limited as to where you could go and who and how you could interact with people.
Questing and exploring would be elements in the game that would fall out, and with the general game design the ES series follows this would kill the game for most people.
Another SI spoiler:
Spoiler Here some might bring up the argument that even if you mantled Sheogorath in the Shivering Isles expansion to Oblivion you coud still go out and explore, but there are some fundamental differences to takign Sheogoraths place and to become the Emperor.
1: Sheogorath is the ruler of a realm of Oblivion, and time doesn't have the same meaning. This is something the Old Sheogorath mentions.
2: You have an Immortal man named Haskil who is either designed(as in created, or chosen by, Sheogorath to have the power to assist him in keeping the realm relatively stable.
This is a being who, by all intents and purposes, can temporary take the role of Sheogorath when he needs to. As an Emperor in Tamriel you will not have that advantage.
3: The Shivering Isles is the realm of Sheogorath, which means it bows to his will, hence the option for exploration is much more believable.
An Empire in Tamriel is not a realm that bows to the Emperors will, but instead the Emperor have to make his decitions based on what the world require of him.
That is just my two cents.