Na, but it should have more negative effects in large doses (and it should have more
positive effects in small doses). Like it should increase speechcraft if you just have a couple of bottles, but drastically reduce it once you start getting truly drunk. I know there's no hit connection stat, but if there was then that's something that should decrease.
All in all there's little point in them programming these effects so long as there's no real reason to drink it in the first place. It'd be great if there were "Dutch courage" bonuses to give us some incentive to consume alcohol.
The effects of drinking certain things could be improved - but personally I find the "drunk-ness" in games really annoying. GTA4 was bad. Red Dead was ok. The only game where I enjoyed it was a level in Saints Row 2 where you were drugged and had to fight your way back home. But for all these reasons, best to keep it out of ES.
That cutscene was priceless if you gave your character the Cockney accent (traditional slang heavy London). Yeah, I loved the effects for that mission. The way you accidentally shot your way out of certain death was very well put together - underappreciatedgame, that.