Not unless the Empire discover that it can be used to undercut another market. If that happens it will be criminalized and lots of propaganda about how it's worse than the hardest skooma.
If you get what I am saying. Reefer Madness.
I tried watching the original Reefer Madness once. It was too boring. If I want beautiful black and white propaganda, I'll go with the other hilarious 50's ones. Or that weird one where Winnie The Pooh not just talks about stranger danger, but... certain touching. Or I'll watch some old 50's B-grade horror film instead. Who needs propaganda when you got swamp monsters and Godzilla?!
I still could see Sleeping Tree Sap becoming illegal. Seems skooma is nothing compared to Khajiit coke... I mean moon sugar. Man, I wish I never found out moon sugar is a term for cocaine.