Call of Duty 1 was the best, afterwards... eh. I'll pass. None of the games have ever come even close to being as good as the first one. Not by a long shot.

Mass Effect is now dead to me. I'll never play another game in it. Just finish it up (extended) and then never look back. It's over...

Final Fantasy
Gran Turismo

• TES - Skyrim just didn't do much for me at all, and with the direction the series is heading in, I can't see myself getting overly excited about TES VI.
  
• Total War - still enjoy the games, but haven't loved a TW game since Medieval 1. Rome was the start of a gradual decline in my opinion.
  
• Medal of Honor - everything after Allied Assault has been poor. I think competing with COD really killed the franchise.
  
• GTA - IV wasn't a bad game, but I didn't enjoy it anywhere near as much as III, VC, or SA.

Final Fantasy

Mass Effect - I've heard this called a series before, but I'm pretty sure it was just one game. Yep, just one great standalone title that never got any sequels.

Sonic the Hedgehog - Poor guy has had a few good games recently (Colors, Generations), but those haven't done much to change my opinion of the series in general, which lost me after Sonic Adventure 2.

Star Ocean - I never really loved Star Ocean, but the first two games were pretty good and I can't really say the same about Til the End of Time and The Last Hope.

If by TPS you mean Third Person Shooter, you should know that Resident Evil 4 actually revolutionized the TPS genre. Up until then the "over-the-shoulder" mechanic was completely unheard of. Many other games like Gears of War extended upon this idea with the cover system (among other things) but Resident Evil 4 was the first.

I can't think of any game series I don't love anymore. I guess I could say TES lost some of it's spark to me, but I still play it occasionally.

Skyrim is too shallow.