I have a few here...
1. It said in the loading screen tips that Giants are USUALLY friendly.. So, taking that to heed, I went up to one. What did he do? Smashed his club into me, killing me instantly, and sending me 500+ feet into the air... Fail collision physics, least I got to see the entire area... LOL.
2. I was doing the quest where I had to get evidence that this guys brother had been kidnapped and I didn't have the best sneaking skill... Eventually I got tired of it and just decided to go for it. Well the only person to see me was a kid and he kept saying "Get outta here, get outta here, get outta here" over and over. I ran into a bedroom, shut the door, and stole the book I needed. When I went to open the door he came in and sat in front of me so I couldn't get out saying "Get outta here, get outta here, blah blah blah" so I shot him in the face with an arrow. He just acted like nothing happened and walked out of the room. I only got a bounty of 40 and just walked out of the house

(Reloaded after cause of bounty, though). Also, he was detecting me when my sneak thing said noone could see me..