I have tested these "fists" and enchanted them and the enchants WORK, and can be refilled using soul gems! Unfortunately I have been unable to get posions working with them, make them upgradeable, or utilize weapon perks.
So here is what I am looking for from the modding community=
1. Allow these "fists" to be upgraded via the sharpening stone DONE! Thanks to Eldiran
2. Allow enchanting in-game and not just using Sky Edit Done! Thanks to Eldiran
3. Classify these fists as 1 handed (or 2) to utilize perks etc. (i have made this work, but the animations change) Done! Thanks to Eldrian
4. Allow posioning of these fists
I will keep fooling with them and seeing what I can do, but modders more skilled than I should definately take a look at them. The fact that these "fists" are enchantable with Sky Edit and that the on-hit enchants WORK holds great promise for unarmed!
EDIT---
Updated post, lets keep up the good work! =)