I just saw this in the news:
http://www.usatoday.com/tech/gaming/2010-08-10-fallout10_ST_N.htm
Newton joins a marquee cast that includes Matthew Perry (Friends), Zach Levi (Chuck), Kris Kristofferson, Michael Dorn (Star Trek: The Next Generation) and Felicia Day (The Guild). Ron Perlman (Hellboy) serves as the game's narrator, a role he has played in several Fallout games, including the 1997 original.
Wow, never expected Kris Kristofferson or Michael Dorn or Felicia Day but I was very happy to see Ron Perlman and half expected that one.
http://content.usatoday.com/communities/gamehunters/post/2010/08/fallout-new-vegas-increases-its-talent/1
Michael Dorn (Star Trek:The Next Generation) returns as Marcus, an intelligent super-mutant, last seen in 1998's Fallout 2
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Hoping this isn't old news.