You can see the sign in the background of the second developer's diary at about 1:36.

It's right when you drive into Vegas strip now guys. Not on the highway anymore at least. Like right where the casinos start. Not the old strip.

The sign you mention...I went to Vegas when I was younger, I recall it being on the road side, the sign you show in the game screenshot is not the same sign. I'm sure I've seen the in game sign equivalent during one of the recent movie clips.

Lucky Bastard

I'm pretty sure it'll be in-game. It's iconic of the new game. It'll probably be a bit outside the strip.

The sign is in the game. From the Dual Shockers interview linked on another thread here

Chad (DS): What are some of the famous Las Vegas area landmarks that we can look forward to seeing and possibly exploring in New Vegas?

Chris (Obsidian): Vegas is Fallout Vegas, not real-world Vegas. While there are some hooks to the Vegas we know and love (Vegas Vic, Wayne Newton, the classic Vegas sign), this is Vegas as envisioned by people in the 50s… as they viewed Vegas of the future…and then bombs dropped everywhere but there. People looted the “lucky” city in great rioting mobs, rebuilt it, and then repopulated it, making it a slightly uncomfortable brightly-lit shadow of what it once was.


It will probably say "Welcome to New Vegas" but it is the same sign.

http://i976.photobucket.com/albums/ae242/davetbeau/newvegas.jpg

I knew I saw it in an ingame video. Kudos for finding this

Keep in mind I posted about this question one and a half months ago, way before the sign was first shown in the Qore preview.