My vote is for this, this should be a poll.
I want this to be more of a discussion, rather than empty numbers.
Anyways, I'm not sure if I voiced what I meant properly. ghoulsrpeople2's post was exactly what I was trying to say. Yes, there are more cities. Yes, there are more quests. Yes, there are more NPC's with more voice acting and unique backstories. But all this uniqueness only brings out the problems in the game. I'm wandering in the middle of nowhere. Supplies are running low and I'm almost dead. I see a house on an outcropping of rocks. Making my way over there, I'm greeted by a man with an extensive backstory and many conversation directions. But this is where it ends.
That's great that Obsidian has put more "lore" in the game. But if someone's rambling on for 10 minutes about a convoluted string of events, I half expect a quest to come out of it. But it almost never does. Maybe I've just been spoiled, and I realize that not everyone will have something that needs doing. But, to me, this adds to the emptiness of the game.
One of my favorite things to do in Fallout 3 was to explore all the little nooks and crannies. There would always be something, whether it be a note, a body and gun positioned strategically to show a struggle of some sort, or some Naughty Nightwear with an unmarked quest associated with it. There's very little of this in NV. There's an overabundance of real side missions, but almost no little details that really add to the atmosphere and encourage exploring.