First run was normal... Second was HC for the achiv., and now all my runs will be hardcoe.
My best memory of this game is from my first HC run.
I got to the end fight on the the dam... the one where you can't go, and buy stuff after starting... Well I had Meltdown perk, and was being careful to let Veronica get the killing blow on everything close when I was shocked that a bunch of (badies) jumped out beside me... I got a shot off at his chest so as not to kill him, and some how hit his head. He blew up (and so to a few of his friends), and crippled head, chest, left arm, and both legs... I tabbed, and to my shock I had only packed two doctor bags! I went through the rest of the fight with my vision going in and out, and slowed with two broken legs.
The only thing I don't like is that companions are killable, and slightly retarted. If I go for a snipe, and miss, and get the (caution) indicator saying someone is on to me, and decide to hide it out my companion should not decide to suicide rush the target

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