Have to agree on doctors. They feel somewhat unbalanced at the moment. For example, my newly made character has little in the way of medicine skill or barter, and is charged over 100 caps for a stimpack which, after damage, will restore something like 18 health. For the same number of caps a doctor can heal me 100%. I'd suggest perhaps a couple of things:

1) Make doctors restore only ~10% health & limb condition for 100 caps (I'd prefer this), or else boost cost significantly
2) Increase the effectiveness of stimpacks - with heavier damage in the early game, taking a single bullet costs me 500 caps worth of stimpacks, leaving me virtually confined to snipe/sneak tactics. Or putting the difficulty back down Maybe stimpacks could restore more health over a longer period of time or something like that.

Doctors being better than stimpaks (and a lot better) is a good thing in my opinion. Otherwise, there's no real reason to use them instead of just hording all the stimpaks you can find and using them to heal.

That said, going to a doctor should advance time by some amount rather than have it be instant.

I think you're severely overestimating the increases in damage. Keep in mind that the skill change only brings weapons up to their existing potential, and the specific weapon edits only changed weaker weapons. The largest hits you can take are no larger than they were in vanilla. The only things that are going to one-shot the player are high explosives, and that only if unarmored. Also, as damage goes up and health goes down, each additional health point has increasing marginal value because there's less of a surplus buffer.

-Doctor's Bag lasts a long time for me. Really long. is this supposed to be the case? Is it a non perishable item?

Is there any plan on changing this, maybe in a separate module somewhere down the road? As mentioned before I've been playing an explosives character with this mod, and I'm kind of disappointed that with light 10 DT armor, 100 Explosives and two ranks of +20% Explosives damage perk, I can still shoot a mini-nuke at my feet and not die. Admittedly I am End 10, but still...

Deadlier Combat
- Increased DT reduction from melee/unarmed skills from 5 (at 100 skill) to 10.
- Energy Weapons skill bonus changed from crit to up to 10 DT reduction (at 100 skill).
- Reviewed and rebalanced all energy weapons (including uniques).

Reduced Wealth
- Further reduced random food loot from 50% to 33%
- Increased rads on uncooked meat.

Healthier Healing
- NPC doctors no longer heal directly, but instead apply a Doctor's Bag and Blood Pack. The player must then rest to benefit.
- Doctors' treatment for radiation takes effect over time (-17 rads/sec)
- Doctor's Bags, Blood Packs, and Hydra provide feedback messages confirming they were applied or failed to apply.
- Stimpacks no longer deal delayed HP damage, but instead immediately damage fatigue.
- Messages will warn when the player is nearing unconsciousness due to fatigue damage (regardless of the source of fatigue damage.)
- Fatigue pool no longer increases with level (but does still increase with Endurance.)