In regards to point 6, I have a GTX 580 with an i5-2500k @ 4.2Ghz and I have a constant 60fps everywhere with vsync, even in Whiterun with 30+ Texture Mods. These are my settings, try and use them yourself and report back here if you want me to help;
1920x1080
Latest Nvidia Driver
uGridsLoad = 7
Ultra-settings but with Shadows on High (IMPORTANT!)
AA and FF OFF in Skyrim Launcher, 32 x CSAA & 8 x SuperSampling and 16 x AF in Nvidia Control Panel (NCP)
Single Display Mode and Prefer Maximum Performance in NCP
Texture Filtering =Clamp
Texture Filtering = High Quality
Ambient Occlusion = On (Performance) - (Turn Off for extra 8fps)
No other Ini tweaks whatsoever.
Other tips
Defrag HDD
Use Skyboost R4
If you are experiencing FPS issues still then turn Ambient Occlusion OFF and make sure Shadows are High. If High is too much change to medium, it hardly makes any difference.
Please come back with your results, your computer should handle this game easily.
Well, after downloading 290.53 and following your tips (Did all except the ugrids) I averaged 52 FPS in Markarth and the lowest drop was 30 FPS in the worst spot I could find in the city. Top of Dragonreach overlooking whiterun: 46 FPS. It seems that your fix (And skyboost) worked. I thank you good sir.


