I would love to see how they implemented the Dragonbone weapons myself, also if they're doing anything special with the werewolves or just saying "Heres a perk tree, enjoy".
Dragonbone weapons will be stronger than Daedric. Shame, because now I feel compelled to unlock Dragon smithing despite only have 11 perks left to spare. Along with them will be crossbows and bolts (arrows as well?) crafting, don't know if crossbows are material-specific.
Werewolves...seems like it's mostly just a perk tree, though I'm just going off the E3 coverage.