I see Skyrim's skooma as a water-down version to Cyrodiil's skooma 200 hundred year ago.
Although the effects from the drugs aren't the same, this is like how all these people are buying acid that is some other synthesized formula and the're like oooh I feel something off four blotters, where if they were taking pure LSD they would be tripping off nanometers.
Haha Skooma is heavily cut and stepped on before it reaches Skyrim nowadays....
EDIT:
Damn i miss buying forty bottles of skooma from shady sam, drinking them and moving at like 300 speed, one-hitting guards..... Ah the days. Of course my intelligence was so bad i could only cast one flare before i ran out of magicka...
I wish I had tried this. I still own Oblivion but it no longer wants to run even after a complete reinstallation.