1 ... no to the ugrid game
2 ... can't get to start a new game,
3 ... didn't really want to do that, reload thing, but a totall reinstall on the game, only use 18 mods, and there not that heavy mainly the horrorview sixy stuff and dues mons plus the riverwood town upgrade,
and signatures turned up out of the blue, may thats a how many post ya do thing
I would suggest the following, to eliminate any corruption and to make a fresh game.
Uninstall Skyrim.
Delete the Skyrim folder, located in Steam/Steamapps/Common
Backup somewhere else, then Delete the Skyrim folder located in My Documents/My Games/
Uninstall Nexus Mod Manager, or whatever utility you use for mods. Also unsubscribe from any subscribed mods on Steam Workshop.
Uninstall all Nvidia software including PhysX etc
After all of these, and a fresh system:
Install the latest Nvidia driver.
Install Skyrim.
Do not add any mods, changes to your ini files, or set any 3rd party software like D3DOverrider or MSI or Nvidia Inspector to do anything with Skyrim.
Launch the game. It will set your graphics settings. Do not change them. Just get in the game and try and start a new game.
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If it finally works, go ahead and make your changes and mod additions etc. But just a couple at a time.