2. Repair isn't as useful as it used to be, no need to TAG it at all. Same for Speech, lines requiring high Speech aren't compulsory at all in the first part of the game and even if a new line appears most you need is 50 or so. Barter isn't very useful because if you scavenge much vendors will be running out of caps to pay for the guns you've looted. No need to TAG any of those, just keep looting and you will be rich.
3. Good TAGs are Science and Lockpick because those skills you want up very fast to open safes and locked doors for XP and loot. Pick third according to your liking, preferably with weapons you are intending to use so you don't need to invvest there until your normal skills are up. I'd advise taking Guns first, then learning other two to some medium levels but in the long run this tag doesn't matter much.
4. Traits were a no-brainer for me. +20% accuracy from trigger discipline makes up for low gun skills and you will only have trouble with gun jamming for 2s every once in a while. Action Points you get from Kamikaze make up for low Agility and allow to do enough close-up VATS devastation to never have trouble in corridors where you can't snipe.
5. As far as Perks go, with Comprehension and Educated you won't need to stretch yourself too much to pass majority of skill tests, just initially train things like Science, Medicine, Lockpick or Speech up to 55 and carry a magazine that can upgrade it to 75 if there's a place needing it so high.
6. After that you want to either boost your criticals to deal more damage from far away with sneak attacks - or boost your VATS skills with more accuracy and Action Points. And in general care rather for damage output than anything else.
7. Companions are godly. My favourite team was Boone and ED-E. ED-E is in Primm and makes up for low perception with his great scanners and all you need to fix him is a bunch of easily acquired parts (Scrap Metal, Scrap Electronics and Sensor Modules), Boone from Novac can kill pretty much every creature you want him to kill and do it in handful of shots. Even those armored Radscorpions are two shots for him. So instead of gun skills, just get Boone and let him do the killing until you get yourself proper weapons. He doesn't use ammo so he can save you quite a few bullets.
8. Guns. The best normal gun you can find early on is .357 Revolver called Lucky which is in the floor safe of the Gift Shop of the bandit hotel in Primm. 75 lockpick needed and there's a skill book there too. Another good gun is Ratslayer, unique Varmint Rifle in Broc Flower Cave (prepare to be radiated and rushed by rats there, bring Boone!). In the long run you want to discover Sniper's Nest near Cottonwood Cove (up on the rocks), there's a case there requiring 100 Lockpick so if you are going with a Sniper, you want his Lockpick at 80 + Comprehension quite early.
9. Energy weapons. First of all, you want a Laser Rifle with a Scope. Upgrades spawn randomly in stores so you want to discover a number of shops with them and then just make a trip searching for this upgrade between them. If you don't find, sleep 73h (shops refresh ev ery 3 days) and make another trip until you find it. Best pistol is Plasma Defender which is a unique Plasma Pistol. You can steal it from Freeside Silver Rush store, just run up north and use Stealth Boy to snatch it off the counter, it will have 100% conditions.
10. Ammo is easy to get, from stores and from conversions (learn to use the bench, learn what ammo types can be converted to another). Guns are easy enough to repair on their own, you find so many on raiders and such that it allows you to keep your stuff at 100% even if your Repair is 15. If you are using Energy Weapons you might want to go high in Repair early on and grab everything you need to manufacture Weapon Repair Kits (memorize what you need for those!), it's hard to fix a Plasma Defender because you won't find many in the game - and paying a professional to do it will cost thousands of caps.
11. Food and drink are only useful in hardcoe. If you aren't playing hardcoe, just memorize recipes for Stimpacks and your favourite drugs of choice (Psycho) and that's it.
12. Roads are safe and at level 2 or 3 with some cunning you can easily make it to Las Vegas to discover the best stores in the game (Gun Runners, Silver Rush). Equipment there is very expensive - but ammo isn't and upgrades are plenty there. So consider going south from Good Springs, east through Nipton and then north all the way up to Vegas East Gate to find those.
13. (I know I promised 12 but this one is kind of useful) Get a room in Novac and stash stuff there in the safe. Don't sell "Misc" stuff unless you know it's 1. not used for any recipe 2. used in recipes you don't want to use.
Rebalances required in future patches:
- Weaker companions. They should have level restrictions so you don't use them for combat to win everything for you too early.
- Perception and Charisma need a place in the game.
- More perps with energy weapons and sniper equipment - so you can repair those if you use them. Better sight range and speed for monsters. Lower, much lower general accuracy.
- More dangerous roads. Only actually tough spot is between Nipton and Novac - but once you know there are dudes on the rocks there you can easily win it.
- Gun skills should influence accuracy more, in VATS very close and outside of it when sniping. Most things on the map I can hit in the head with Guns skill at 15 at range of 5km and kill instantly with a sneak critical. And most things in buildings I just use VATS to headshot and crit-kill.
- More random monsters on the map!
