Focusing on sneak, bow, light armor, illusion and destruction magic and one handed (daggers). My dunmer vampire has been terrorizing all kinds of towns. I sneak in and kill guard after guard with my bow from afar. I also like to sneak in and slit their throats with my dagger. Too many people use vampiric drain as their main offense weapon before "softening" up their prey. I find after wounding them with arrows they die so much easier with this power. Then of course I love using the other vampire gifts like raising a body to fight for me and calming a enemy only to slit their throat, fun times.
Vampires are suppose to be stealthy killers of the night, not raging forces of destruction, like the werewolves are. Play them right and man are they fun.

i cant believe i didnt catch that when i was typing!!