I only ever take the steel and arcane smithing perks (if at all), it's more about how you play in most situations. I imagine I could do it on master with a heavy armor, block, 1h, conjuration and restoration character, I've never died on my level 60 character on master, don't even have full armor rating at that level.
I imagine if I played DiD I would die because I'd be to careful ha, can't be bothered to do that though.