I will have magic in one hand or both hands and a one handed weapon in another hand. What one handed weapon will depend on the enemy I'm fighting and how good the weapon is.
For my Nord Character - Left hand: Spell. Right hand: Hammer. For my Dark Elf Character: Both hands spells. For my Orc Character: Both hands swords/hammers.
I used to like playing an unarmoured mage who would fall back on hand to hand - I'm not so sure what the weapons will look like this time round - I'll probably go for a light sword - I hope they have Dai-katanas again
Umbra when/if I find it. Been my primary weapon in both Morrowind and Oblivion, and that's a tradition I want to continue. Failing, a claymore or some sort or dual wield swords.