Be careful about dropping filled Soul Gems: there have been reports that if you drop filled Soul Gems they are emptied when you drop them - I guess the soul escapes. Some have reported that even storing them in containers will empty them. I've never dropped them, but I have stored them and so far stored ones have retained the souls.
Hey Buckom

I've stored hundreds of Black and Grand Soul gems filled with a Grand soul, in various House chests. I've also dropped a lot of filled Grand Soul gems, to use as decoration and I've never had to deal with "escaped souls"

(yea, I'm on PC).
That would be interesting to see if there are 500K individual coins laying in a pile or if it's represented by one huge coin purse.
I've dropped 500 gold before and it IS just ONE coin lol I dropped it in front of some beggar's feet, hoping he would pick it up, but noooooooooooo, guess some of the "RADIANT AI" isn't quite that radiant. LOL
OK back to Fallout New Vegas forums!

@ the OP: Wow, that is a weird bug. In all the time since release, nobody ever mentioned anything like that. I wonder if that bug crept into the game via one of the patches. I've stored Gold before, in the safe in the Solitude House, because I just had too much and I wanted to go back to being poor LOL I also started to pay my 'help' (House carls) and stored gold in their inventory. I never had any issues once I retrieved it. However, playing TES games, one certainly knows NOT to store items in Barrels.

It's strange though that even your new game is affected by that bug.
Are you on PC? Have you tried to clear the game cache through Steam?