His quest is named after the old song "Eddie my Love". So I'd think his name would be pronounced "Eddie"
That's what I'd assume too, plus, it seems to be a common trope in fiction for robots and AIs to have names that are an acronym for something (As ED-E is as well.) but just happen to spell out what sounds like a name a real person might have. While in this case, the acronym doesn't actually spell out "Eddie", or any other name, it could potentially be pronounced that way, I'd say that's most likely how it was intended to be read. Still, I usually just think of the name as being pronounced like the letters "E" 'D" and "E". In other words "EE DEE EE". It just seems more appropriate for a robot that in no way resembles a human and is silent except for the occassional beeping and playing music when a threat is spotted. Giving a robot a normal sounding name seems more appropriate when said robot seems a little more... human, like say, Victor. Sure, that robot doesn't look human, obviously, but between having a voice, being programmed with a fairly distinct personality, and that cartoon cowboy face on the screen, he still feels much more human than an Eyebot. Besides, when a name like ED-E is pronounced as "Eddie", it tends to make me think of a certain Pixar movie.
Come to think of it, I think I'd have preferred if the robot companion was a Securitron rather than an Eyebot, but that's beside the point.
He was taught by the nice boys and girls of the Followers of the Apocalypse.
Of course, there's no guarentee that their knowledge is completely accurate either. Though judging from the fact that I recall Arcade Gannon also spoke at least one Latin phrase once, they obviously have some information on the language.
I tend to think of Caesar, when used as the name of the leader of Caesar's Legion, as being pronounced the way most people in the Legion pronounce it, though. Primarily because I like the sound of it better than how others pronounce it. Besides, since Caesar chose to use that name himself, he gets to choose how to pronounce it, and that's obviously the pronunciation he chose to use. But that's a different matter.
If it's pronounced ee-dee, then wouldn't that be "she?"
I'm sorry, but my ED-E is a girl. Seriously, high pitched "voice?"
Totally a chick.
I don't know, I have a hard time thinking of ED-E in feminine terms. And while ED-E is usually just referred to as "it" in the game, I'm pretty sure I recall one instance of "he" being used to refer to the robot, so if I were to assign any gender to ED-E, it would be male.