
Summary
Mage does the most damage out of anyone, achieving 160,232 damage, requiring two attacks to apply the poisons, drinking of three potions, two of which are in a specific order and then casting Blizzard. More work than other characters to achieve that damage but it is incredibly high. If anyone wants me to try something else let me know. I left out a lot of details but enough is here if anyone else wants to try it and verify it.
Apparatus
- Apprentice stone
- Weakness to Frost poison: Ice Wraith Teeth + Fire Salt
- Weakness to Magic poison: Salt Pile + Scaly Pholiota
- Potion of Fortify Heavy Armor (self weakness to Frost): Ice Wraith Teeth + White Cap
- Potion of Regenerate Magicka (self weakness to Magic): Dwarven Oil + Jazbay Graqes
- Potion of Fortify Destruction: Glowing Mushroom + Nightshade
- A weapon to apply the poisons (Bow works)
Gear to craft potions:
- Falmar Helmet: Potions are 29% more powerful
- Circlet: Potions are 29% more powerful
- Ring: Potions are 29% more powerful
- Amulet: Potions are 29% more powerful
- Gloves: Potions are 29% more powerful
With the above, you create the following potions:
- Weakness to Frost poison: Target is 110% weaker to frost damage for 30 seconds.
- Weakness to Magic poison: Target is 74% weaker to magic damage for 30 seconds.
- Potion of Fortify Heavy Armor (self weakness to Frost): Increase Heavy Armor skill by 74 points for 60 seconds. Target is 88% weaker to frost damage for 30 seconds.
- Potion of Regenerate Magicka (self weakness to Magicka): Magicka regenerates 184% faster for 300 seconds. Target is 59% weaker to magic for 30 seconds.
- Potion of Fortify Destruction: Destruction spells are 184% stronger for 60 seconds.
Participants
Whiterun Guard at the entrance to Whiterun with 200,000 health. Use console command "setav health 200000" to achieve this.
Formula
Blizzard (with +50% perk, applied twice and likely a bug)
+ Apprentice stone
+ Reduce Magic resist (potion to self, multiplied by Apprentice stone weakness)
+ Reduce Frost resist (self, multiplied by weakness to magicka for even larger boost)
+ (Weakness to Magic poison (on enemy) - Enemy Magic resist)
+ (Weakness to Frost poison (on enemy, NOT multiplied by reduce magicka resist) - Enemy Frost resist)
+ Fortify Destruction
+ Fortify Destruction (due to bug or intended?)
= 45 + (100 + (59 +100% = 118))% + (88 + (100 + 118)% = 279)% + 74% + 110% + 184% + 184%
= 45 + 218% + 279% + 74% + 110% + 184% + 184%
= 45 * 3.18 * 3.79 * 1.74 * 2.1 * 2.84 * 2.84
= 15,983.9 per second AOE
= 159,839 damage after 10 seconds AOE
Procedure
- Activate Apprentice stone on self
- Find target, increase their health via "setav health 200000"
- Hit target with magic weakness poison
- Hit target with frost weakness poison
- Drink reduce Magic resist potion, exit inventory screen to let potion apply
- Drink reduce Frost resist potion, exit inventory screen to apply
- Cast Blizzard
NOTE: Order of 3. and 4. can vary as they do not stack in the same way as applying to self. However, applying Magic weakness to self before Frost weakness to self is necessary as the Magic weakness further boosts the Frost weakness. i.e. 88% Frost weakness to self becomes 279% Frost weakness to self if you have Apprentice stone (100%) and Magic weakness to self (59%... which then becomes 118% due to Apprentice stone). Thus Frost weakness to self 88% + 218% = 279% which you can verify in game UI.
Results
After performing the above procedure on the Whiterun guard I brought his health from 200,000 to 39,767.44.
My test was predicting a result of around 159,839 damage but the real test showed 160,232 damage. I am not sure what could be the reason but it is so close that there could just be some margin of error in that the spell runs for slightly less than intended.
EDIT: With correction to base damage and Testing on Adept rather than Master difficulty.


, swords aren't as stealthy as daggers though. Then power attacks, or dual wield power attacks will be crazy high damage.