I could never be with a man who considers me secondary to his calibrations.
Jennifer Hale does a great job on voicing FemShep, a much better job than Mark Meer does on MaleShep. Now that is some bland, soulless voice-acting!
As for the original post, the idea of a role-playing game is to be someone who is not you, and play their role. I'm male all the time, so why not play a female character? Plus that way I can spend hours in the character generator getting her face just right, so I can have a completely customized model when drawing her. It's got nothing to do with juvenile horniness or any other Freudian nonsense.
I always assumed Garrus skills at "calibration" :hubbahubba: would come in handy.

Oh who am I kidding... all the romance options for a femshep are soooo cheesy that it induces giggles in me when I even see an option on the dialog tree.
I have to say that I really like Jennifer Hale's VA, but Mark Meer totally grew on me - when I play as the male Shepard, I just assume that the voice - that sort of clueless occasional wise-assery mixed with a does of being a total [censored] on many occasions makes Shepard who he is. And the delivery of "It's a big stupid jellyfish" in ME1 always makes me crack up for five minutes. He's kind of so bad he's good and I could not picture the male shepard with a different voice.
Back on topic'ish, there are times I have had a great deal of fun playing a male character. In The Witcher, one of my favorite games, I had a grand time making Geralt a complete hound dog. I was playing at the same time as some guys on this forum and I think they were pretty entertained at my project of making sure Geralt got laid by every possible character he could.

I know some women were offended, but eh, it's still a game and female characters like Triss and Sh...whatever her name was, were pretty strong in their own right... if hilariously susceptible to Geralt's dubious charm.

I ended up preferring my male Lone Wanderer in Fallout 3, to the female one as well - no idea why, but I got into that role a bit more than when I ran through it as a female. :shrug:
It's why I like games - I get to do random stuff, play as random characters...