Definitely the lighthouse with the family that had been eaten by chaurus.

That house which was attacked by a dragon, inside only a note was for the local authorities reporting a dragon sighting... their bodies were burnt to a crisp and their house torn to bits.

Since this is a spoilers forum..
I have yet to go to the lighthouse but the saddest moment for me is when I killed the Emperor's cousin during the DB quest. It was a cheerful, bright day and a nice day to have a wedding. She was kind to me and what does she get? A knife in the back just for the sake of the DB, i was very doubtful after and it was a very hard moral choice to do it.

The couple who were eloping.

An ancient dragon burnt http://www.uesp.net/wiki/Skyrim:Seren to death. Nobody mourned for her, not even her husband. Her charred body froze into the snow & ice at the town's border. She was expecting a child I've also fetched a book to help'em raise the child in both redguard and nordic ways.

I found a giant doing that. I think it might have been a glitch though... maybe?

Mine is also Meeko. I am constantly reloading cause I keep accidently killing him.

When I lost Janessa to a couple of bandits just outside Whiterun after we'd fought all manner of fiercer opponents. I thought I'd accidentally put an arrow in her, but when I loaded an earlier save I made sure I didn't hit her and she died again, in exactly the same spot. She was my first follower in Skyrim, but I'm happier with her replacement, Faendal, who stays back most of the time and uses ranged attacks. However, he did accidentally off me with an arrow intended for a bear I was fighting which dropped a split second before he let one fly!

Has anyone else been accidentally killed by their follower?

Rrreeeeally....

I was walking down a random road and found a dead couple. After snooping around I found a journal, and how the guy saved money/jewels for a long time in order for them to be able to be together and get married. I thought that to be sad, as he was sucessful but they died during travel. I put their bodies under a tree and threw down a couple flawless diamonds and emeralds around their bodies.

Does anyone know where exactly this lake is? I've been trying to visit the place but I can't find her. Is her body directly south of Solitude, in the marshes where there are lots of mudcrabs and chaurus?

The Merchants outside Dragon Bridge, reading the wife's journal and how she was so worried about her husband's safety, that she goes with him and both end up killed.

The lighthouse thing, definitely.

The journals were heartbreaking. I cursed myself for not arriving earlier. I wish there was a way to do so.

Hey everyone. First post weu

By far the saddest event for me to even watch was when Kodlak had died. I come back and there's silver hand all over the place and immediately my heart had dropped. I go inside and I see Kodlak and I couldn't believe it. I never put so much hate on myself before on a game. I constantly wanted to think that I could have saved him. I reforged Wuuthrad and from there on I killed every silver hand till I was content.

Or when your about to kill Aldiun and you see that guard and he is just so hopeless and says Alduin will get you. I'd look behind me and I saw a huge dark figure swoop down and get him. Skyrim is by far a true heartbreaker of a game. It really does get to you.

Probably when I found out about Rustleif and Seren expecting child, doing the quest for them so that the child could know something about its Redguard homeland, then having a dragon show up and kill them both.

Needless to say, I reloaded many times until I could defeat the dragon without them getting killed.

I just rescued a prisoner from his Thalmor captors on the road to Markarth from Rorikstead. I'd done this before in the past, but I'd always seen the prisoner getting jumped and dying to some hostile encounter along the road, so this time I decided to try it out differently.

I shadowed him all the way past Whiterun, saving him from two sabre-cats and three bandit thugs before he charged at yet another sabre-cat. Needless to say, it killed him :/ I felt terrible that they always die, so I laid his body on the pelt of the cat and spent a couple of minutes http://steamcommunity.com/profiles/76561198054502464/screenshot/613846549769228984?tab=public.

That's really sweet of you.

For me it was the lighthouse near the college of Winterhold. Those people scraqed up the money to buy the place and moved there to start a new life with their kids. Then they all got captured by the Falmer, some of them were eaten, some [censored] (I think) and one committed suicide.

I enjoyed taking revenge for them though.

When i read about Falmers and how they ended up such a hideous monsters.
I felt sorry for their fate.

Traveling some dungeon with Kharjo (the Khajit companion) he got mauled by some vampires and draugr and fell on his knees. I, wielding a bow, started shooting over his head at the enemy. When he recovered he ran to the right out of my view, and then when I was preparing to finish out the last vampire he rushed in front of me, right there in front of my arrow and got shot in the head just after turning around to look at me. The arrow went in just above his left eye, he fell on his knees and his head fell back 45 degrees as if he was looking at me. It was quite grueling.

The chaurus ravaged lighthouse and Meeko were pretty moving, as well as the dozens of journals and cannibals I've come across... but for me it was Clavicus Vile's quest.

Dog's just tug at my heart strings, and actually being able to kill the little bugger (or let him live) moved me. Even in Vile's twisted rationale, he still just wants his best friend back with him.

A commentary on friendship, and the vampires longing for a cure during the quest was sort of sad as well.

Indeed. Barbas just wanted to be with his master and Vile asks you to kill him. So I figured I'd piss Vile off and refuse. I found it amusing about the vampires wanting a cure and then all of a sudden I rushed in and killed them all.

Then, you go back to Lod and tell him the dog was more trouble than he was worth, and he doesn't care either. I dunni how you can go one minute wanting a loyal companion, next minute saying "**** it".

Also Daedra see death differently since they are immortal. Vile points out that hes not dead, and will be back in like 200 years. In the meantime he has some peace and quite. =D

Finding dead Link, why cruel world why!?

This a thousand times.

Words cannot express the eternal sorrow in my heart.

We will never forget the great. Rest in peace, Lurbuk, the second greatest bard ever, second only to Lissete of the Winking Skeever.