As a supporter and avid fan of SkyRe, I feel compelled to post here, as this mod, and it's intentions have been rather misrepresented. I do not believe Skyrim requires "saving", however, it could do with some polish and a few internal reworking, and SkyRe intends to do just that.
At its core, SkyRe is an overhaul, no amount of modularity (of which it has quite a significant amout) will change that. So if you prefer vanilla Skyrim, and your taste in gameplay mods is confined to small tweaks, this mod is not really for you (although maybe one or two of the modules may still interest you, so I encourage you to check them out if you have the time). If, however, you enjoyed the heck out of vanilla Skyrim at first, like I did, but eventually started to feel bored by the system that encouraged power gaming perk choices and the infamous crafting skill loop, without actually presenting you with any challenges befitting your newfound awesome power, like I did, then this mod (in its entirety, or as many modules as you wish) may very well be exactly what you need.
SkyRe - Main overhauls almost all perk trees (I never really played a mage in vanilla, so I can't speak to the magic perk trees) in order to create more variety, more (and, more importantly, more interesting) choices, and remove or change perks that provided little to no benefit. Prominent features include different perks for different weapon types (scimitars, katanas, longswords, shortbows, longbows, to name only a couple), and Shouting integrated into Speechcraft, with perks to increase shout effectiveness and let your shouts scale with your skill. It also adds several fun new spell mechanics, including auras and plagues that spread among enemies. There are a lot more spells and tweaks to existing ones, but like I said, my characters are rarely mages, so I'm not the best person to describe these (although I must admit, SkyRe has greatly encouraged me to add a few choice spells to my sneaky and warrior type characters' arsenals). Another feature is the introduction of Timed Blocking, which I'm sure most of you remember from Deadly Reflex. The main module also fully includes and integrates Weapons of the Third Era.
SkyRe - Races contains changes to races (quelle surprise). Almost all racial abilities are changed or swapped out. Again the design goal here was (I assume) to remove weak and lacklustre abilities and replace them with cool stuff you actually want to use. Check the description for specifics.
SkyRe - Combat modifies the way combat works. There are already a few mods out there which cover this, in a variety of different ways. In my opinion, in this case, more options are a good thing. This module offers stamina based attack damage, blocking efficacy, and movement speed.
SkyRe - Enemies features customized enemy scaling and AI, minimum level for encounter zones, and relveant perks for enemies.
SkyRe - Standing Stones tweaks standing stones.
SkyRe - Lighting adds Pokémon to Skyrim, and replaces the main theme and all other music with "Gotta Catch 'em All". Or maybe it just changes lighting, I forget.
SkyRe - Vampirism merges the Pickpocketing and Lockpicking tree into a new tree, called Fingersmith, and polishes it up a little. The free perk tree slot is then used for a brand new Vampirism skill tree.
For more detailed descriptions of the modules visit the SkyRe - Skyrim Redone nexus page, the link is in the first post.
All in all, if you want your next Skyrim playthrough to no longer be more of the same, but instead want to add a little spice, a little flavour, a lot of variety, and a boatload of fun, then I highly encourage you to try SkyRe!