I wouldn't mind some Star Wars references. Perhaps a laser rifle that, when in the hands of the enemy, is horribly inaccurate, but when in the hands of your party members(And your own hands I suppose) it's highly accurate? Perhaps the Falcon crashed outside Primm? Mysterious Stranger has a minute chance of being replaced with Han?
No Lightsaber. The way they work is very strange. What tells the beam to stop at a certain point? They're too ridiculous even for Fallout.
Actually the blade containment is so simple it could be done right now with real world tech. It's a simple magnetic field affect that keeps the plasma in check. Building the devices needed to do this isn't feasible on such a small scale but it can be done, no different than how you'd contain the plasma in a Fusion reactor.
Though the generation of such plasma beam remains pretty ludicrous.