http://www.gamesas.com/topic/1341234-unofficial-patch-14-pc-issues-thread/
Some Notes first:
The Released Patch has the same version number as the Beta Patch. The final Beta is what was released. If it does not appear that your game is updating, make sure you have the game set to update in Steam and Steam in Online Mode. Also, you may need to Verify the File Integrity if the patch does not seem to be taking hold. Steam may update the game if you were part of the Beta as the this is retired.
Quests
Note, the Quest Fixes as noted in the patch notes should work on an existing save. However some game conditions and data are part of the save and may still not work post patch. Load your current save and try it and see what happens. If it does not work, try loading a save from before you got the quest, if practical, and it should work just fine.
Mods
The patch is only for the as shipped game from Bethesda. If you try to launch the game post patch with any mods selected and you have issues, the first suspect are the mods. Disable any and all mods and try the game again. The patch can and will break some mods. If you are using any mods, you will need to check each and every mod for updates for the new patch. Add them back one at a time until you find the problem mod or mods. You may need to use the various mod tools like Wrye Bash on your mod mix again once you get the mods sorted. Just remember, new patch and mods, it is probably the mods. Look to the mods section for reported issues on the mods you use. Search first over there before posting a thread.
Performance and Stability Mods, also known as Wrappers or Code Injectors, are not compatible with the new patch. So those will have to be removed. They are also not really needed anymore. Those authors may update those mods at some point. There are threads on TESVAL and Skyboost and similar in the mods section discussing what is going on with those mods.
Script Extenders such as SKYSE (Skyrim Script Extender) and Script Dragon have or will be updated to the new patch, so check for updates to those. Check the Skyrim Mods section if you have any issues with your mods under the new patch.

