So far, the cazadores have been much more dangerous than the deathclaws. The cazadores move much more quickly and their flight pattern makes them difficult to shoot from a distance. One hit is all it takes for them to wipe me out. With deathclaws, if I am using a melee weapon, I can block their attacks and often knock them down using the super slam perk.
I have Rad Child, so if there are not too many deathclaws attacking me at once, I can regen the small amount of HP I lose when they hit me if I am blocking, but the cazadores kill me every time. I have yet to figure out a way to move past the areas where Cazadores hang out, but I can sneak around the deathclaw areas relatively easily.